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Khaliya
Tuesday, Dec. 12, 2017 · 9:04 a.m. · 16m 36s
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00:00:02
hi
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thank you for that very maybe in the introduction so yeah um
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ladies and gentleman at an on air and a privilege to be here today
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i will preface this the net parents by saying the opinions uh might harker entirely my own
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uh and do not necessarily reflect that the conference as a whole and i say that not because they asked me to
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or because what i'm about to say is anything disagreeable but rather
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bit that my commentaries curse or for me to you
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and in the context of a sorry for me to you and in
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the context of looking towards a bright future for grain and mental
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health for all uh_huh so you may be asking yourselves wildest sex and
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gender matter to explain uh let me start with the story
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when i was little my mom asked me to draw what i wanted to be when i grew up
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never someone short of imagination i drew we're not one but three things that
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i wanted to be a a fireman about arena and the psychologist
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i grabbed a very progressive house her parents didn't what will
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just feel like my identity was dictated by societal norms
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such as rolls around arenas and ways of firemen so
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whenever i was given toys it was always boat
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so different part of me wanted to be the strong firemen the
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graceful ballerina and the person who heals people by listening
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my mum was a psychologist and i was i was impressed in all the fact that people would come to her to get better
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but she was in her own way saving the world one person at a time
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when in individual at a time through listening and asking the right questions
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no i never did and that being a ballerina which is obvious if anyone of you have ever seen it yes
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but i end up becoming in some ways but the psychologist and the firefighter of sort
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i got a degree in public health and used it to listen to and ask the right questions about epidemics of illness
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and right now it is epidemics of mental health issues that are reaching global proportions
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growing like an out of control fire in desperate need of some firefighters to put it out
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depression is now the leading cause of disability worldwide according to the h. o.
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over three hundred million people are estimated to suffer from depression
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and between almost a million a year commit suicide
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and between two thousand and ten and twenty fifty the
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cumulative global economic output associated with mental have
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is projected to be sixteen trillion us dollars
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approximately the same amount as the entire u. u. s. g. d. p.
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in fact in this room is statistically probable that one in ten of you are on what some sort of antidepressants
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and that one out of every four people suffer from mental illness at some point in your lives
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as the writer rita mae brown one set take a look at your three best friends
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if they're okay i mean it's you are but seriously
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everyone in this room is in some way affected by mental health
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or bring health issues themselves or via a loved one
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every year fifteen million people suffer stroke of which six million died in five
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million or left permanently disabled it is the second leading cause of death
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and to mention the sky rocketing there an estimated forty seven million people living with dimension two thousand fifteen
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and this number is expected to double every twenty years reaching seventy five million in twenty thirty
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and a hundred and thirty million people in twenty three fifty if nothing is done
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to give you some perspective on that figure that is more people than in all of japan
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and addiction is on the rise eighty percent of the global opiate supply is
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consumed in the united states were painkillers or twenty four billion dollar market
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and what are two of the top three highest consume trucks
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painkillers and antidepressants
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prescription opiate sales in over dude overdose deaths are up four hundred percent in the last ten years
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and on average one in three women would be the victim of sexual assault
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we're talking one every two minutes or seven by the time i talk is over
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thirteen percent of these rape victims attempts suicide and many of them are like p. g. s. d.
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and many many the refugee populations in victims of word they recently had when a new term
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to describe the severity of the mental distress experience because they've l.
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p. t. s. d. did not appropriate the disk right
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the brain's reaction to seeing parents killed homes destroyed and streets strewn with bodies
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women are often the hardest hit by these that's okay she's it is estimated that eighty percent of the
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fifty million people currently affected by violent conflicts civil
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wars disasters and displacement or women and children
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and on the more safe turf such as the us well one in three americans
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who struggle with the mental illness this figure is forty percent higher in women
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women in general are twice as likely to experience clinical depression there are also
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two times as likely to develop p. t. s. d. is man
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there are some serious for what we doubt the depression gap hormones social pressures in a significantly the fact that women
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experience vastly higher levels of violence and abuse as evidenced by
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some of the staggering rate statistics i mentioned earlier
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so what can we do and how can we help
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many of the factors that make women more vulnerable are environmentally are socially constructed
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and some to maybe biological but looking at it more simply as in the
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metaphor of the fire there some simple practised is to putting on fire
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one by the tool that can put it out which is the holes but squirt water
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and to find out why the fire started so you can start stop it from starting again
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so how can we apply this to remains brain in mental hell
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well firstly to put out the fire this epidemic we need
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to look at the tools that we're using because you can't put out a fire with the hose full of the air
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in this instance not only do we need to dive deeper and do more appropriately
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constructed clinical trials to to youth outreach in response difference isn't sex and gender
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but further i think we need to re examine some of our fundamental theories
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on what does and does not work with respect to mental health
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and expanded clinical trials on a greater scale to new and emerging tools
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we need to figure out where we can stop hours before they start
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by lowering the overall rates of depression suffering in our midst
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pain begets pain when a mother is depressed the child suffers the family centres
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similarly when males depressed immensely and well he's more likely to engage
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in antisocial behaviour such as violence domestic abuse and substance use
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which just proportionally effects females in turner and also can lead
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but also can lead to tearing of societies very fabric
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so just incidence of mass violence which is almost exclusively perpetrated by males
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but is simply another way like depression
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manifesting an underlying mental injury
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i use the term mental injury quite specifically here because they believe most
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people that are currently scene is mentally ill or actually just injured
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all they need is the chance to heal with the right tools so that it is no longer something chronic
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other way in both cases by not putting out the fire word starts
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at the individual level the fire pros and impacts the collective
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people left to sell for untreated or poorly he'll eat it
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become reservoirs and factors of illness in our midst not because they want to be
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but because they can't seem to put out their own fires and
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we e. so far have been unable to help them
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why
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well because many of the tools we currently employ simply aren't working
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recently there was of you review of thirty eight clinical trials comparing various treatments for depression
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what the review found out was that placebos were three times as effective as no treatment
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especially in more so if they had side effects which is in some ways right
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but and here's the interesting part antidepressants work only marginally better in
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fact placebos were seventy five percent as effective as prescription antidepressants
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diving deeper into on published f. t. i. clinical
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trials the review conducted by irving hirsch examines
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the six most widely used antidepressant drugs between nineteen eighty seven and nineteen ninety nine
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i and prozac axles so lost a lexus arizona and effects are
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and found that the c. was we're actually eighty two percent as effective as the dross
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when measured a lo oh by the hamilton depression scale also known as the handy
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the average difference on the handy was only one point
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eight points which well statistically significant is clinically meaningless
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which explains why even extra treatment for mental illness has exploded still to have epidemics of
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mental health reason in concert are those quite simply is not putting out the fire
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what does that mean that we might as well be using placebos or
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is there something else something that actually works that we could use
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i believe the answer is that there is and that is not only the reason
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why i am here speaking to you today but it is also the how
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because i too was once debilitated by mental injury i had been
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the victim of a violin rubbery that left me shatter
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nightmares cold sweats panic attacks literally overnight i went from
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a strong vibrations woman too broken version of myself
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and this lasted for several years
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it wasn't obvious on the outside i was pretty good writing it but no matter what i did i just
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couldn't shake it it was like a contract it varies with you your and no hope for relief
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i tried everything all of the regularly prescribed drugs talk there the exercise their meditation you
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name it but i simply could not get back to the way i mean
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and then i found out about some interesting research they were doing using a class of drugs that had once been seen as
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a promising class of compounds but that had become not just
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stigma ties to the criminal lust for decades psychedelic us
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now for those of you not familiar with the term a psychedelic is loosely defined anything that alters perception
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in this case i'm are trying to things like and you may also notice access your molly a
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lusty commonly known as acid hiding they ah and suicide and also known as magic mushrooms
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it sounds crazy this idea of using such powerful compounds once people suffering from mental issues
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it makes it so easy to dismiss any view they're out there they're sceptical i know how hard wired we are
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to think that these compounds are nothing but trouble literally playing with fire rather than putting out the fire
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line here is living proof to tell you that the students work
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when i decided to try to take my let myself in my own hands i did
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so out of desperation and frustration and i knew i was taking a risk
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but i also had seen it with my own eyes people utterly transformed in
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a positive way when it was done according to the proper protocols
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and is both the scientist and stuff for had to see what it was all about how to see if it would work
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and it it so well in fact that i rarely if ever suffer any of the symptoms of p.
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t. s. d. that i used to have on a daily basis quite simply it saves my life
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and like the lights properly used have the potential to save the lives of how close others
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why because it's like dialects to something better current go to psychiatric drugs not
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transforming hardwired neural patterns to reroute the very architecture of the brain sometimes in a single doze
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wrong griffiths a professor of the in the department of psychiatry neuroscience is that john hopkins
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as like an second oh it's ability to bring about what i
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call neural routing as they can to a surgical invent intervention
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similarly it is said that a single doses so was tied in the compound in magic mushrooms
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can do in thirty seconds what it takes antidepressants three to four weeks to do
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according to david not professor your your sector pharmacology at imperial college london
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and a study published in the journal of cycle pharmacology on people with anxiety associated with life
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threatening illness suggested that alice d. assisted psychotherapy was
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successful in almost seventy percent of subjects
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with the positive effects lasted more than a year and causing no adverse reactions
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and then there's and you may which just this year received breakthrough therapy status from the f.
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t. a. for the p. treatment of p. t. s. d. which is what i had
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breakthrough status essentially means that combined with the regiment of therapy it can potentially do what no other job
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in the market is capable of doing and in this case is well the numbers speak for themselves
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the most recent batch of trousers on people with p. t. s. d. so severe that they've been suffering with the condition
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for for more than seventeen years on average seventeen years
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and the studies show that when i'm jim it was used as part of us like that there'd be treatment effects risking changing
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one year after treatment seven out of ten of the people no longer suffered from this condition
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by comparison only two out of ten people with p. g. s. d.
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find relief not healing but relief from traditional psychotherapy under psychiatric medications
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but m. g. m. is is to take that their p. peers not only to provide short term relief but
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remote such long lasting changes in the brain that some patients are actually in fact short like me
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for sure these earlier results with small sample sizes but clearly
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we're on to something and this is just the beginning
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there are so many things that contribute to act epidemics of illness and tackling the issues of
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sex engender in science are clearly things that we must do for the sake of science
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but for the sake of humanity i urge you all to consider changing the norms that perpetuate violence
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especially against women and then once that allow the festering of mental issues unabated that is one
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of the things that we need to do if we are to address this epidemic
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because one small fire can quickly become a bigger one but if
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we can actually healed mental injuries one by one individual by
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individual we can people the firemen and this like when a list and keep the fire from growing out of control
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everyone here has the power to change this dynamic in open up new productive feel to think
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worry it doesn't have to be slightly dialects but we definitely need some new tools
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please help me find them so maybe one day we want all have to be psychoanalyst and firefighters
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are there will be less fires to fight unless people meeting how and then
Conference Program
Welcome Words
Maria Teresa Ferretti, President, Women's Brain Project
Dec. 12, 2017 · 8:48 a.m.
Welcome adress
Françoise Grossetête, member of the European Parliament
Dec. 12, 2017 · 8:55 a.m.
Presentation of the day
Sylvia Day, Forum host and WBP ambassador
Dec. 12, 2017 · 9:01 a.m.
Introduction of Elena Becker-Barroso
Elena Becker-Barroso, Editor-in-Chief of The Lancet Neurology
Dec. 12, 2017 · 9:21 a.m.
231 views
Introduction of Gillian Einstein
Gillian Einstein, University of Toronto, Canada
Dec. 12, 2017 · 9:28 a.m.
Introduction of Else Charlotte Sandset
Else Charlotte Sandset, Oslo University Hospital, Norway
Dec. 12, 2017 · 9:39 a.m.
Introduction of Carol Brayne
Carol Brayne, University of Cambridge, UK
Dec. 12, 2017 · 9:44 a.m.
Introduction of Maria Teresa Ferretti
Maria Teresa Ferretti, President, Women's Brain Project
Dec. 12, 2017 · 9:52 a.m.
158 views
Introduction of Liisa Galea
Liisa Galea, University of British Columbia, Canada
Dec. 12, 2017 · 9:56 a.m.
Introduction of Lawrence Rajendran
Lawrence Rajendran
Dec. 12, 2017 · 10:03 a.m.
245 views
Introduction of Thorsten Buch
Thorsten Buch, Director, Institute of Laboratory Animal Science (LTK), University of Zurich, Switzerland
Dec. 12, 2017 · 10:08 a.m.
Introduction of Meryl Comer
Meryl Comer , President & CEO, Geoffrey Beene Foundation Alzheimer's Initiative
Dec. 12, 2017 · 10:59 a.m.
Introduction of Mary Mittelman
Mary Mittelman, New York University School of Medicine, US
Dec. 12, 2017 · 11:05 a.m.
Introduction of Angela Abela
Angela Abela , University of Malta, Malta
Dec. 12, 2017 · 11:13 a.m.
Introduction of Tania Dussey-Cavassini
Tania Dussey-Cavassini, Former Swiss Ambassador for Global Health, Switzerland
Dec. 12, 2017 · 11:20 a.m.
480 views
Introduction of Rajendra Dhamane
Rajendra Dhamane
Dec. 12, 2017 · 11:29 a.m.
Introduction of Sofia Petersson
Dec. 12, 2017 · 1:23 p.m.
Introduction of Raj Long
Raj Long , Bill and Melinda Gates Foundation, Vice-Chair, World Dementia Council
Dec. 12, 2017 · 1:30 p.m.
201 views
Introduction of Antonella Santuccione Chadha
Antonella Santuccione Chadha , Swissmedic, Swiss Regulatory Agency, Switzerland
Dec. 12, 2017 · 1:32 p.m.
371 views
Introduction of Marsha B. Henderson
Marsha B. Henderson, Food and Drugs Administration, Office for Women's Health, US
Dec. 12, 2017 · 1:36 p.m.
Introduction of Maeve Cusack
Maeve Cusack, European Institute for Women's Health
Dec. 12, 2017 · 1:43 p.m.
Introduction of Hadine Joffe
Hadine Joffe, Harvard Medical School, US
Dec. 12, 2017 · 1:47 p.m.
Introduction of Maria Houtchens
Maria Houtchens, Harvard Medical School, US
Dec. 12, 2017 · 1:55 p.m.
Introduction of Valerie Bruemmer
Valerie Bruemmer, Senior Medical Advisor, Eli Lilly
Dec. 12, 2017 · 2:03 p.m.
Introduction of Malou Cristobal
Malou Cristobal, Polytrauma/ TBI / Vestibular Rehabilitation Program, New York Harbour
Dec. 12, 2017 · 2:08 p.m.
Panel Discussion: Sex and gender in clinical trials for brain and mental diseases – Reconsidering the way we test drugs
Dec. 12, 2017 · 2:12 p.m.
113 views
Wrap up of Panel Discussion 3
Raj Long , Bill and Melinda Gates Foundation, Vice-Chair, World Dementia Council
Dec. 12, 2017 · 3:23 p.m.
Presentation of Sofia, Robot
Sofia, Robot
Dec. 12, 2017 · 3:28 p.m.
Introduction of Nicoletta Iacobacci
Nicoletta Iacobacci , Singularity University Geneva
Dec. 12, 2017 · 3:32 p.m.
Introduction of Fabrizio Renzi
Fabrizio Renzi, Innovation and Technologies Director, IBM, Rome
Dec. 12, 2017 · 3:36 p.m.
Introduction of Joanna J. Bryson
Joanna J. Bryson , University of Bath, UK
Dec. 12, 2017 · 3:48 p.m.
Introduction of Myshkin Ingawale
Myshkin Ingawale, Facebook
Dec. 12, 2017 · 3:58 p.m.
Introduction of Kathryn Goetzke
Kathryn Goetzke, President, Chief Mood Officer & Founder, The Mood Factory, and Founder, iFred
Dec. 12, 2017 · 4:07 p.m.
Introduction of Nikolaos Mavridis
Nikolaos Mavridis , Interactive Robots and Media Labs, MIT, US
Dec. 12, 2017 · 4:13 p.m.
Panel discussion: Digital biomarkers and new technologies – New tools to support women's brain health
Dec. 12, 2017 · 4:26 p.m.
Closing remarks
Mara Hank Moret
Dec. 12, 2017 · 5:12 p.m.
605 views
