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gonna be again about alzheimer's disease uh like to do things better
00:00:04
for this beautiful overview of it it became a logical aspect
00:00:08
and the point that i would like to add the um again just a couple of words i don't have slides but i wanted to make sure
00:00:14
that is audience would appreciate the complexity of the issue of sex and
00:00:18
gender for a fantasy so we heard it in a logical part
00:00:21
and they're the topic that i would like to bring to you and for you to keep
00:00:24
in mind for the future discussions is the topic um of the affinity peak variability
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so uh a specialist women's been project and a research activities that we've been conducting in the
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past year we've been really focusing on this aspect because we think sex and gender
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might affect not just the beast and the numbers of patients that are affected by alzheimer's disease and the men so
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but even the way this is manifest itself so we're talking about seems
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we're talking about the question we're talking about but i'm not
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indeed usual phonetic variability is absolutely crucial because alzheimer's disease
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it's a very complex disease and and it is a very high level of it it's in eating the patients
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um so people have different manifestation even with the same level even patients that are
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by marcus tactile rice with the same level by markers you with that
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certain patients that are stable certain patients that have very that
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connected the klein some will decline faster some slower so
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there are additional factors that we're missing out and i think the point i would like to
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bring to they might become messages that facts might be a very important driver affinity peabody
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and there are some evidence in the literature in the sense so we do know um that there are
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differences in the performance and verbal memory for instance which is heavily used for diagnosing a sense disease
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women out there for many this task but then when the disease kick seen um
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somehow decline even faster so that could be something important to look at
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um we have a difference is in the b. b. b. hey the manifestation of alzheimer's disease women
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tend to be more the press men tend to be more aggressive so different therapeutic treatment there
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um in terms of by your markers that the evidence is still fast we do
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not have really evidenced that women have more or less on lookers now
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but the relationship between the level of by you might use in then the the clinical manifestation of the disease
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that's something where we had some uh they thought the show that this relationship is all somewhat related by sex
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which i think is crucial when we're talking about diagnoses and set
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up a um research um discourse or cutoff values we might
00:02:30
going the direction of i think um sex sensitive or a a diagnostic tools
00:02:37
institute for uh the the risk factors as well so that i respect those are for that time is
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is is that we know uh the they they're gonna become for both men and women but me
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we're not considering that families factors might be might have behaviour impact on men than women
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or vice versa so also the team but of saxons and and this but
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so all you know that would like to to to keep in mind this idea affinity peak variability and that sex
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might be a major driver of these in this could have an impact in the way we diagnose the disease
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in the way uh we try and prevent the disease in in the way we are we treat the disease
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that are not so many data on this topic and i'm personally with the
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women's been project and on a mission to convince everybody to go back
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to their databases and just tell us if when you stratified data by sex
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you do see something because we have tons of information right now that it's been collected about there
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has not been a focused on certification of data by sex uh so we basically have
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you know so so so much research that we can do and i encourage everybody who's working in
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this field to really go back to their data set analyst and stratified them by sex
00:03:44
come back and tell us what you see and it's really the right moment to talk about this and even to publish
00:03:49
is also what we're trying to do to help finding journals that i can publish these days

Conference Program

Opening
Gautam Maitra, Founding Member, Women's Brain Project
Dec. 12, 2017 · 8:45 a.m.
168 views
Welcome Words
Maria Teresa Ferretti, President, Women's Brain Project
Dec. 12, 2017 · 8:48 a.m.
Welcome adress
Françoise Grossetête, member of the European Parliament
Dec. 12, 2017 · 8:55 a.m.
Presentation of the day
Sylvia Day, Forum host and WBP ambassador
Dec. 12, 2017 · 9:01 a.m.
Keynote
Khaliya
Dec. 12, 2017 · 9:04 a.m.
Introduction of Elena Becker-Barroso
Elena Becker-Barroso, Editor-in-Chief of The Lancet Neurology
Dec. 12, 2017 · 9:21 a.m.
230 views
Introduction of Gillian Einstein
Gillian Einstein, University of Toronto, Canada
Dec. 12, 2017 · 9:28 a.m.
Introduction of Else Charlotte Sandset
Else Charlotte Sandset, Oslo University Hospital, Norway
Dec. 12, 2017 · 9:39 a.m.
Introduction of Carol Brayne
Carol Brayne, University of Cambridge, UK
Dec. 12, 2017 · 9:44 a.m.
Introduction of Maria Teresa Ferretti
Maria Teresa Ferretti, President, Women's Brain Project
Dec. 12, 2017 · 9:52 a.m.
157 views
Introduction of Liisa Galea
Liisa Galea, University of British Columbia, Canada
Dec. 12, 2017 · 9:56 a.m.
Introduction of Lawrence Rajendran
Lawrence Rajendran
Dec. 12, 2017 · 10:03 a.m.
242 views
Introduction of Thorsten Buch
Thorsten Buch, Director, Institute of Laboratory Animal Science (LTK), University of Zurich, Switzerland
Dec. 12, 2017 · 10:08 a.m.
Introduction of Meryl Comer
Meryl Comer , President & CEO, Geoffrey Beene Foundation Alzheimer's Initiative
Dec. 12, 2017 · 10:59 a.m.
Introduction of Mary Mittelman
Mary Mittelman, New York University School of Medicine, US
Dec. 12, 2017 · 11:05 a.m.
Introduction of Angela Abela
Angela Abela , University of Malta, Malta
Dec. 12, 2017 · 11:13 a.m.
Introduction of Tania Dussey-Cavassini
Tania Dussey-Cavassini, Former Swiss Ambassador for Global Health, Switzerland
Dec. 12, 2017 · 11:20 a.m.
477 views
Introduction of Raj Long
Raj Long , Bill and Melinda Gates Foundation, Vice-Chair, World Dementia Council
Dec. 12, 2017 · 1:30 p.m.
198 views
Introduction of Antonella Santuccione Chadha
Antonella Santuccione Chadha , Swissmedic, Swiss Regulatory Agency, Switzerland
Dec. 12, 2017 · 1:32 p.m.
370 views
Introduction of Marsha B. Henderson
Marsha B. Henderson, Food and Drugs Administration, Office for Women's Health, US
Dec. 12, 2017 · 1:36 p.m.
Introduction of Maeve Cusack
Maeve Cusack, European Institute for Women's Health
Dec. 12, 2017 · 1:43 p.m.
Introduction of Hadine Joffe
Hadine Joffe, Harvard Medical School, US
Dec. 12, 2017 · 1:47 p.m.
Introduction of Maria Houtchens
Maria Houtchens, Harvard Medical School, US
Dec. 12, 2017 · 1:55 p.m.
Introduction of Valerie Bruemmer
Valerie Bruemmer, Senior Medical Advisor, Eli Lilly
Dec. 12, 2017 · 2:03 p.m.
Introduction of Malou Cristobal
Malou Cristobal, Polytrauma/ TBI / Vestibular Rehabilitation Program, New York Harbour
Dec. 12, 2017 · 2:08 p.m.
Wrap up of Panel Discussion 3
Raj Long , Bill and Melinda Gates Foundation, Vice-Chair, World Dementia Council
Dec. 12, 2017 · 3:23 p.m.
Presentation of Sofia, Robot
Sofia, Robot
Dec. 12, 2017 · 3:28 p.m.
Introduction of Nicoletta Iacobacci
Nicoletta Iacobacci , Singularity University Geneva
Dec. 12, 2017 · 3:32 p.m.
Introduction of Fabrizio Renzi
Fabrizio Renzi, Innovation and Technologies Director, IBM, Rome
Dec. 12, 2017 · 3:36 p.m.
Introduction of Joanna J. Bryson
Joanna J. Bryson , University of Bath, UK
Dec. 12, 2017 · 3:48 p.m.
Introduction of Myshkin Ingawale
Myshkin Ingawale, Facebook
Dec. 12, 2017 · 3:58 p.m.
Introduction of Kathryn Goetzke
Kathryn Goetzke, President, Chief Mood Officer & Founder, The Mood Factory, and Founder, iFred
Dec. 12, 2017 · 4:07 p.m.
Introduction of Nikolaos Mavridis
Nikolaos Mavridis , Interactive Robots and Media Labs, MIT, US
Dec. 12, 2017 · 4:13 p.m.
Keynote
Lynn Posluns , Women's Brain Health Initiative, Canada
Dec. 12, 2017 · 4:52 p.m.
Closing remarks
Mara Hank Moret
Dec. 12, 2017 · 5:12 p.m.
600 views
Thanks
Annemarie Schumacher Dimech
Dec. 12, 2017 · 5:16 p.m.
Closing song
Sylvia Day, Forum host and WBP ambassador
Dec. 12, 2017 · 5:23 p.m.