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00:00:01
thank you it's great to be here so i am actually metallic i'm senior scientists
00:00:06
politics from trade by training at the most international or in d. s. l.
00:00:13
estimated seventy percent of smokers trying to wait but only six percent sixty
00:00:20
so this means that over a billion people will continue to smoke in the near future worldwide
00:00:27
smoking is addictive it causes fatal disease it's time for new era in tobacco industry
00:00:34
and p. my score for harm direct reduction is to develop new
00:00:38
products that have the potential to reduce the risk of smoking
00:00:43
and also to collect rubber scientific evidence to demonstrate that
00:00:47
these products indeed are safer for the consumer
00:00:51
now in p. m. i. r. in danish that l. we have hundreds of scientists and engineers that apple
00:00:58
needed to develop new novel products as well as as as their safety any impact on biological systems
00:01:06
one way to reduce the far is not to burn a two part well but uh just heat
00:01:12
and these grass your show on the left conventional cigarette small all the chemical compounds it consist
00:01:19
and on the right you have a one version of a reduced was product
00:01:23
as we call them or the iris or from reduced the product
00:01:27
now in addition to developing the products and trying to make sure that
00:01:31
the chemicals really need are reduced we also do rigorous assessment
00:01:37
we used toxicology lab approaches using laboratory models
00:01:41
we have clinical studies we do consumer perception and want torn follow up for the products
00:01:50
now i will present the departmental systems toxicology and our aim is
00:01:54
really to conduct experiments on biological systems where we compare
00:01:59
the convention or product with the r. p. and try to demonstrate
00:02:03
that indeed the impact on the biological system is reduced
00:02:07
and we use mechanism based approaches quantitative approaches that we ought we have developed a good deal of developing further
00:02:14
we also tried to understanding the process more mechanistic information about
00:02:19
cardiovascular disease chronic obstructive palmer disease and lung cancer which are really related to smoking
00:02:27
now we have many scientific disciplines aptly my are in d. we have these these
00:02:32
experts we have web lab scientists we have experts in different technology platforms
00:02:39
we have computational scientist buying from additions physicists who develop computational
00:02:45
models to analysts and interpret the data from our experiments
00:02:49
and we also have biologist that bill network models for um to do the product assessment
00:02:55
and now we had six internships at philip morris and you can find these and your e. p. f. l. portal
00:03:02
and five of them are actually in my department systems toxicology and
00:03:06
peace um please go and take a look at these

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Conference Program

Welcome
Marc Gruber, VP Innovation, EPFL
16 March 2017 · 9:04 a.m.
1,161 views
Logitech
Jean-Michel Chardon, Logitech
16 March 2017 · 9:07 a.m.
560 views
Intro of S. Gautsch
Marc Gruber, VP Innovation, EPFL
16 March 2017 · 9:21 a.m.
Context and Logistics of the Industry Day
Sebastian Gautsch, STI-EPFL
16 March 2017 · 9:22 a.m.
219 views
Master Thesis in Industry Context
Pierre-André Besse, Adjunct VP Education, EPFL
16 March 2017 · 9:34 a.m.
171 views
Role of distributed energy storage in smart grids 
Mario Paolone, Distributed Electrical Systems Laboratory - EOS Holding Chair
16 March 2017 · 9:39 a.m.
123 views
Materials and nanostructures for next generation photovoltaics
Anna Fontcuberta, Laboratory of Semiconductor Materials
16 March 2017 · 9:46 a.m.
138 views
Medium Voltage High Power Electronics
Drazen Dujic, Power Electronics Laboratory
16 March 2017 · 9:50 a.m.
390 views
Ubiquitous high performance PV energy scavengers in all shapes and colors : from IOT to buildings 
Christophe Ballif, Photovoltaics and Thin Film Electronics Laboratory
16 March 2017 · 9:54 a.m.
Highly efficient and clean conversion in fuel cells & electrolysers
Jan van Herle, Group of Energy Materials GEM
16 March 2017 · 9:59 a.m.
103 views
Small electromechanical moving devices 
Paolo Germano, Integrated Actuators Laboratory
16 March 2017 · 10:06 a.m.
Novel actuation methods for reconfigurable soft robots
Jamie Paik, Reconfigurable Robotics Lab
16 March 2017 · 10:12 a.m.
289 views
Revolutionary optical tools for Ophthalmology 
Christophe Moser, Laboratory of Applied Photonics Devices
16 March 2017 · 10:18 a.m.
173 views
Mighty soft materials
Dario Floreano, Laboratory of Intelligent Systems
16 March 2017 · 10:29 a.m.
104 views
Intro words, VP Research
Andreas Mortensen, VP Recherche, EPFL
16 March 2017 · 11:18 a.m.
140 views
The endovirome, source of biomarkers and potentiel therapeutic targets
Didier Trono , Laboratory of Virology and Genetics
16 March 2017 · 11:23 a.m.
114 views
New strategies to fight infections, hidden in the human genome
Jacques Fellay , Fellay Group
16 March 2017 · 11:29 a.m.
Smart Wearables for the Medical IoT Context
David Atienza, Embedded Systems Laboratory
16 March 2017 · 11:33 a.m.
213 views
Rational protein design for vaccine development
Bruno Correia, Laboratory of Protein Design & Immunoengineering
16 March 2017 · 11:39 a.m.
177 views
Medical Image Analysis 
Jean-Philippe Thiran, Signal Processing Laboratory 5
16 March 2017 · 11:43 a.m.
101 views
Advanced Functional Fibers
Fabien Sorin, Laboratory of Photonic Materials and Fibre Devices
16 March 2017 · 11:51 a.m.
197 views
Production of amorphous particles
Esther Amstad, Soft Material Laboratory
16 March 2017 · 11:57 a.m.
144 views
Mechanobiology and tissue engineering
Dominique Pioletti, Laboratoire de biomécanique en orthopédie
16 March 2017 · noon
128 views
High Performance Elastomers, Thermoplastics, and Lubricative Coatings
Holger Frauenrath, Laboratory of Macromolecular and Organic Materials
16 March 2017 · 12:06 p.m.
177 views
Simple models for complex flows
François Gallaire, Laboratory of Fluid Mechanics and Instabilities
16 March 2017 · 12:11 p.m.
274 views
Présentation du partenaire Alliance
Roland Luthier, Directeur du Programme Alliance, EPFL
16 March 2017 · 12:17 p.m.
Présentation du partenaire FSRM
Philippe Fischer, FSRM
16 March 2017 · 12:21 p.m.
Présentation du partenaire Swissmem
Philippe Cordonier, Swissmem
16 March 2017 · 12:25 p.m.
Presentation of Innovaud
Jean-Michel Stauffer, Innovaud, Conseiller en Innovation
16 March 2017 · 1:46 p.m.
Arcoptix
Gerben Boer, Arcoptix
16 March 2017 · 1:51 p.m.
204 views
Fast3D
Claude Forin, CEO
16 March 2017 · 1:55 p.m.
Unitechnologies
Denis Bubendorf, Unitechnologies
16 March 2017 · 1:59 p.m.
217 views
Etudiant EPFL
Firmin Manoury, Etudiant EPFL
16 March 2017 · 2:04 p.m.
ABB Sécheron
Pablo Furrer, ABB Sécheron
16 March 2017 · 2:09 p.m.
114 views
Schindler
Martin Kusserow, Schindler
16 March 2017 · 2:14 p.m.
210 views
CSEM
Stéphane Emery, CSEM
16 March 2017 · 2:21 p.m.
274 views
Flyability
Adrien Briod, Flyability
16 March 2017 · 2:30 p.m.
122 views
CEA
Philippe Garrec, CEA
16 March 2017 · 2:35 p.m.
109 views
Meyer Burger / Pasan SA
Vahid Fakhfouri, Meyer Burger / Pasan SA
16 March 2017 · 2:41 p.m.
119 views
Mikron SA
Sylvie Leggiadro, Mikron SA
16 March 2017 · 2:46 p.m.
292 views
Etudiant EPFL
Luc Conti, Etudiant EPFL
16 March 2017 · 2:51 p.m.
Johnson & Johnson
Grégoire Veber, Johnson & Johnson
16 March 2017 · 2:55 p.m.
147 views
Micronarc
Danick Bionda , Micronarc
16 March 2017 · 4:01 p.m.
111 views
Festo
Nicolas Godel, Festo
16 March 2017 · 4:05 p.m.
141 views
Melexis
Caroline Heid, Melexis
16 March 2017 · 4:14 p.m.
259 views
Etudiante EPFL
Sueda Turk, Etudiante EPFL
16 March 2017 · 4:19 p.m.
146 views
Maxon Motor
Olivier Chappuis, Maxon Motor
16 March 2017 · 4:24 p.m.
244 views
Philip Morris
Marja Talikka, Philip Morris
16 March 2017 · 4:30 p.m.
129 views
Radar Swiss
Radmila Belavina, Radar Swiss
16 March 2017 · 4:33 p.m.
Tag Heuer
Cyrill Cattin, Tag Heuer
16 March 2017 · 4:37 p.m.
228 views
Vidi Systems
Reto Wyss, Vidi Systems
16 March 2017 · 4:50 p.m.
220 views
Suss microoptics
Wilfried Noell, Suss microoptics
16 March 2017 · 4:55 p.m.
148 views
Novelis
Gilles Hodel, Novelis
16 March 2017 · 4:59 p.m.
Fischer Connectors
Stéphane Rohrbach, Fischer Connectors
16 March 2017 · 5:04 p.m.
220 views
Etudiant EPFL
Maxime Valdemarin, Etudiant EPFL
16 March 2017 · 5:09 p.m.
118 views
Bobst
Leonard Badet, Bobst
16 March 2017 · 5:14 p.m.
632 views
Frontiers
Stefano Battaglia, Frontiers
16 March 2017 · 5:19 p.m.
170 views
Xsensio
Hoël Guerin, Xsensio
16 March 2017 · 5:25 p.m.
173 views
Closing remarks
Sebastian Gautsch, STI-EPFL
16 March 2017 · 5:30 p.m.

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