Player is loading...
Detection of molecular mechanisms in response to hypoxia and starvation in placental cells
Tanja Restin, USZ, Neonatal department
Tuesday, Jan. 21, 2020 · 2:08 p.m. · 03m 56s
Embed
Transcriptions
Note: this content has been automatically generated.
00:00:00
certain time of human development office and that's the most important organ if the placenta cannot really go into the
00:00:07
supply of nutrients and or oxygen we are talking about
00:00:11
essential in sufficiency finally leading to ensure to improve education
00:00:16
and our objective was to assess what the effects of type oxygen starvation are on to sentence has
00:00:23
and that's why we use to remotes less placenta cell and object three inch ourselves
00:00:29
either in expose them to new i'm marks yeah which means zero point two
00:00:33
percent of oxygen or room here and then either start them them way that um
00:00:40
uh_huh them with or without the colours edition then
00:00:44
we assessed viability d. n. a. content and thirteen amounts
00:00:48
and on the red plot you see it after after the uh
00:00:51
results of viability of the four hours eight hours and twenty four hours
00:00:56
and the first lot the uh circles in white it's normal to occur
00:01:02
then comes high plucks yeah then normal to us that asian and white box yes their patient
00:01:07
and it's easily visible that type talks yeah alone does not really affect my ability but that
00:01:12
not hard box yeah installations finally
00:01:15
pizzas to a significant decrease of viability
00:01:20
um so you see the image after twenty four hours object ourselves on
00:01:25
the left and you see it nicely the it rolls off the cells in
00:01:32
here to write down below button a ways fact box yeah starvation in combination
00:01:39
and it's similar to is uh due to d. n. a. contents
00:01:43
sell 'em it the longer the cells are exposed to high any
00:01:48
'cause the patient the more reach use the d. n. a. content is this is
00:01:53
also true for protein amount which is reduced to one fourth after twenty four hours
00:02:00
up to now we haven't um detect it it's signalling component being responsible for
00:02:06
that's and that's why we will for the s. s. if
00:02:09
this is the closest up hoses or to a g. going on
00:02:14
and ah question it's
00:02:29
this is a very good question because we know that the children uh are it's a bit details is
00:02:35
kind of a yeah four thousand c. level as so we do not um
00:02:42
directly know what the exact oxygen amount should be in the cellars
00:02:47
so even within the class and i probably there is a gradient accent
00:02:51
but for sure zero point two percent is new and knock sick
00:02:55
so this is not uh the the stitches they normally should have
00:03:00
it is quite difficult to assess what what is the normal condition
00:03:07
good because you you don't compare normal to be possible to put part boxer would type provokes your costume
00:03:14
one hundred and fifty you mixed work review to disprove influence these results
00:03:21
or some two different groups so we discuss whether we should
00:03:25
probably then incubate is it directly at the lower amount of oxygen
00:03:30
to assume that there is a link with layer covered on top
00:03:33
of the cells which also in here the oxygen transfers we then decided
00:03:38
to go oh or this easy approach in order to know what yeah yeah what
Conference Program
Welcome words
Matthias Roth-Kleiner, Lausanne
Jan. 21, 2020 · 10 a.m.
162 views
Welcome words
Andreas Malzacher, St. Gallen
Jan. 21, 2020 · 10:01 a.m.
Altered brain metabolism contributes to executive function deficits in children born very preterm
Barbara Schnider, Department of Pediatric Intensive Care and Neonatology, Kinderspital Zürich
Jan. 21, 2020 · 10:07 a.m.
1759 views
Early assessment of "shift of the SpO2 vs. PiO2 curve" predicts bronchopulmonary dysplasia in extremely preterm infants
Ben Stöcklin, UKBB
Jan. 21, 2020 · 10:18 a.m.
156 views
Music in preterm infants enhances maturation of neural pathways involved in Emotional Processing
Joana de Almeida
Jan. 21, 2020 · 10:27 a.m.
140 views
Parental self-efficacy and Quality of Life is reduced in parents of late-preterm children
Tanja Restin, USZ, Neonatal department
Jan. 21, 2020 · 10:50 a.m.
191 views
Perinatal palliative care services and needs of health care professionals working in Swiss perinatal centres - A nationwide survey
Manya J. Hendriks, Newborn Research Department of Neonatology, Perinatal Centre, USZ
Jan. 21, 2020 · 10:59 a.m.
205 views
Preterm oral feeding – beyond reflexes
Nicole Kaufmann, ICBCLC, Logopädie, Ostschweizer Kinderspital
Jan. 21, 2020 · 12:10 p.m.
298 views
Plasma mr-pro-atrial natriuretic peptide and ct-pro-endothelin-1 is associated with respiratory morbidity in very preterm infants
Roland P. Neumann, Department of Neonatology, University Children’s Hospital Basel UKBB
Jan. 21, 2020 · 1:52 p.m.
Physical activity programs for promoting bone mineralization and growth in preterm infants
Sirée Kaempfen, UKBB
Jan. 21, 2020 · 1:55 p.m.
Characterization of the acoustic environment in a neonatal intensive care unit
Mikael Martins Gaspar, Faculty of Mechanical and Process Engineering, ETH Zurich
Jan. 21, 2020 · 1:59 p.m.
Detection of molecular mechanisms in response to hypoxia and starvation in placental cells
Tanja Restin, USZ, Neonatal department
Jan. 21, 2020 · 2:08 p.m.
First report of a neonate girl with imperforate hymen and congenital urethrovaginal fistula
Sonja Fontana, Division of Pediatric and Adolescent Gynecology, University Children’s Hospital Zurich
Jan. 21, 2020 · 2:12 p.m.
248 views
Large congenital hemangioma causing significant cardiac and respiratory insufficiency
Andrea Peitler, Kinderspital Zürich
Jan. 21, 2020 · 2:15 p.m.
220 views
An unusual cause of hydrops fetalis
Cristina Felice Civitillo, CHUV, Lausanne University Hospital & HUG, Geneva University Hospital
Jan. 21, 2020 · 2:18 p.m.
136 views
Neonatal alloimmune thrombocytopenia and enterovirus meningitis - an unusual combination
Veronika Rings, Department of Neonatology, Spital Zollikerberg, Switzerland
Jan. 21, 2020 · 2:22 p.m.
193 views
Cardiorespiratory events post immunization in extremely preterm infants
Susanne Boettger, Neonatal Department, USZ
Jan. 21, 2020 · 2:25 p.m.
Early Onset Neonatal Sepsis in Africa: Alarming Results from a Systematic Review and Meta-analysis
Flavia Rosa Mangeret, Neonatology Unit, Geneva University Hospitals (HUG) & Institute of Global Health, Department of Medicine, University of Geneva
Jan. 21, 2020 · 2:29 p.m.
128 views
When an elephant hides another one
Varvara Dimopoulou Agri, Clinic of Neonatology, Department of Woman Mother and Child, University Hospital Center and University of Lausanne (CHUV)
Jan. 21, 2020 · 2:33 p.m.
206 views
How confident do neonatologists feel in predicting the long-term prognosis of the extremely preterm children born <28 gestational weeks when discharging from the NICU?
Ulla Jochumsen , Child Development Center, University Children`s Hospital Zurich
Jan. 21, 2020 · 2:36 p.m.
103 views
Prognostic value of placenta pathology in neonates with hypoxic ischemic encephalopathy (hie)
Laura D. Benz, Department of Pediatric and Neonatal Intensive Care, University Children’s Hospital Zurich
Jan. 21, 2020 · 2:40 p.m.
The milk gap: Contextualizing Human Milk Banking and Informal Milk Sharing Practices and Perceptions in Switzerland
Jacqueline Barin, CHUV
Jan. 21, 2020 · 2:45 p.m.
An unexpected and severe complication due to a presumed umbilical venous catheterisation
Markus Hahn, PICU/NICU
Jan. 21, 2020 · 2:47 p.m.
170 views
Severe refractory status epilepticus in a neonate
Claudia Beck, Pediatric and Neonatal Intensive Care Unit, Children’s Hospital of Eastern Switzerland
Jan. 21, 2020 · 2:51 p.m.
105 views
The Red Code: improving patient safety by implementing a new call procedure for emergency life-threatening caesarean section in a non tertiary center
Anne-Sophie Morel, Hôpital de Nyon-GHOL
Jan. 21, 2020 · 2:54 p.m.
Ductus venosus atresia leading to severe hydrops fetalis in a very preterm infant
Sven-Eric Baller, Clinic of Neonatology, University Hospital Zurich
Jan. 21, 2020 · 2:59 p.m.
312 views
Neonatal transport in Switzerland:
Tanja Leemann, University Children’s Hospital Zurich
Jan. 21, 2020 · 3:02 p.m.
103 views
Perinatal Stroke and Placenta Pathology
Francisca Barcos, Service de Néonatologie, Hôpitaux Universitaires de Genève (HUG)
Jan. 21, 2020 · 3:06 p.m.
159 views
Correlation of bilirubin levels with the quality of General Movements in moderate preterms – a retrospective study
David Graßmugg, Medical University of Graz
Jan. 21, 2020 · 3:10 p.m.
192 views
Implementation of multidisciplinary In-House Resuscitation Training at Triemli Spital Zürich
Hanna Seewald, Paediatric Department, Stadtspital Triemli, ZH
Jan. 21, 2020 · 3:13 p.m.
Use of Donor Breast Milk at LMU München Perinatal Centre : Experiences and Results
Julia Kappeler, München (DE)
Jan. 21, 2020 · 3:38 p.m.
Milkbanks in Switzerland
Andreas Malzacher, St. Gallen
Jan. 21, 2020 · 3:59 p.m.
103 views
Feeding in late and moderately preterm infants : risks and benefits in the short and long-term
Nicholas D. Embleton, United Kingdom
Jan. 21, 2020 · 4:22 p.m.
235 views