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00:00:00
thank you very much Christopher this
00:00:02
very very unclear and fascinating talk
00:00:04
with lots of thought-provoking
00:00:07
statements i'm sure there are many
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questions are there any questions in the
00:00:12
audience i was telling us that
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recognition is superior to to dopamine
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yeah and then I probably mr. point that
00:00:28
then you tell us that we should use WT
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mean why not
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norepinephrine well I think you should
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we can use both depending on the on the
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situation where you're in when you have
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higher vascular resistance then you you
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first need something to improve
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myocardial contractility and sometimes
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you it makes sense to use both the rumen
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to increase positive inotropic support
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norepinephrine to try trait the vascular
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resistance
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I think that's individual clinical that
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judgment according to the hammer dynamic
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situation a certain hour of like the
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baby actually usually newborn babies
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usually am especially gram-negative that
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they have high peripheral vascular
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resistance and if I don't hug you into
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the club open on the weekend often given
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cope to question if these are allowed
00:01:34
first regarding this million of study
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and was million monotherapy or was it
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our combined with another drop
00:01:44
well as I as far as i remember well in
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India enterovirus that was monotherapy
00:01:50
the Vietnam trial
00:01:51
yes and in there india dose-finding
00:01:54
studies it was always add onto usually
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epinephrine
00:01:59
ok and the second question
00:02:01
got the food management in sepsis you
00:02:04
said that we should be very close with a
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adeboye char fluids and Drita under
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echocardiographic our control and
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cartography control and what is your
00:02:16
suggestion for the bases are free that
00:02:20
we're giving should we reduce the mass
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play also we need 250 per kilo
00:02:26
how do you do that the basic solution
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you're going well I i wouldn't change
00:02:30
the basic solution we just keep it
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running and then add extra fluid
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according to what you see in the echo
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and if we see already that our heart is
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over loaded with food
00:02:45
well then you should have then you then
00:02:46
of course you should use an eye drop but
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you should do you would do always look
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at the acting out i hope i think that
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because you from the outside it's
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difficult to tell
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okay thank you very much
00:03:01
let's define it want to add a word of
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caution and to make sure that not
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everybody goes home using intoxicated
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the moment because you have to look at
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the numbers in exasperation small it's
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the small studies and most of them are
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from Poland you showed an example where
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very few small studies short and
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positive effect and then there was a
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large RC done and the effect is gone so
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controlling to publication bias and I
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think we need a large country a study
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but I i think it's very difficult to do
00:03:29
such as such a trial because overall
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acceptance which meets extended
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hemodynamic support is a rare we talked
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a lot about this but most babies don't
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have severe sepsis they came they
00:03:43
receive antibiotics a little bit of
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sodium chloride and that's fine
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so the severe sepsis is a rare if you
00:03:49
look at the apple trials even they had
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to have recruited many many centers and
00:03:53
every Center just had two or three cases
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which they added to their to the trial
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and such a try is very very expensive
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because you have to initiate so many
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centers and I don't think that ever
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it's such a trial will be financed at
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least in in the lodge light in in
00:04:13
northern North America or Europe just
00:04:15
too costly
00:04:18
thank you very much i think you're right
00:04:21
mate

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Conference Program

Welcome Words
M. Roth-Kleiner, R. Arlettaz Mieth
Jan. 10, 2017 · 9:33 a.m.
659 views
Short Reports Introduction
E. Giannoni, T. Karen, Resp. Lausanne, Zürich
Jan. 10, 2017 · 9:38 a.m.
138 views
Association of Axonal Injury and Preeclampsia
Katrina Evers, Neonatology UKBB
Jan. 10, 2017 · 9:39 a.m.
307 views
Q&A - Association of Axonal Injury and Preeclampsia
Katrina Evers, Neonatology UKBB
Jan. 10, 2017 · 9:44 a.m.
158 views
Retinopathy of Prematurity
Roland Gerull, Bern
Jan. 10, 2017 · 9:47 a.m.
293 views
Q&A - Retinopathy of Prematurity
Roland Gerull, Bern
Jan. 10, 2017 · 9:54 a.m.
138 views
Parechovirus Infection: A Rare Cause of Neonatal Encephalitis (in French)
Dr Truant AS, Cheffe de clinique, Néonatologie, CHUV, Lausanne
Jan. 10, 2017 · 9:59 a.m.
549 views
Q&A - Parechovirus Infection: A Rare Cause of Neonatal Encephalitis
Dr Truant AS, Cheffe de clinique, Néonatologie, CHUV, Lausanne
Jan. 10, 2017 · 10:04 a.m.
126 views
Genetic Susceptibility to Neonatal Group B Streptococcal Disease
Alessandro Borghesi, Fellay lab, EPFL
Jan. 10, 2017 · 10:17 a.m.
174 views
Q&A - Genetic Susceptibility to Neonatal Group B Streptococcal Disease
Alessandro Borghesi, Fellay lab, EPFL
Jan. 10, 2017 · 10:25 a.m.
Psychomotor Development in Children Prenatally Exposed to Methadone
G. Grand-Guillaume-Perrenoud, Pediatrics, Children's University Hospital Geneva
Jan. 10, 2017 · 10:27 a.m.
170 views
Q&A - Psychomotor Development in Children Prenatally Exposed to Methadone
G. Grand-Guillaume-Perrenoud, Pediatrics, Children's University Hospital Geneva
Jan. 10, 2017 · 10:34 a.m.
Introduction to Christoph Berger's Presentation
C. Kind, R. Gerull, Resp. St.Gallen, Bern
Jan. 10, 2017 · 10:37 a.m.
Vertical Infections: An Update
Christoph Berger, Zürich
Jan. 10, 2017 · 10:40 a.m.
439 views
Q&A - Vertical Infections: An Update
Christoph Berger, Zürich
Jan. 10, 2017 · 11:15 a.m.
Introduction to Eric Giannoni's Presentation
R. Pfister, S. Kämpfen, Resp. Geneva, Basel
Jan. 10, 2017 · 11:44 a.m.
147 views
Sepsis, Antibiotics and Resistances: Where Are We?
Christoph Bührer, Berlin
Jan. 10, 2017 · 2:21 p.m.
271 views
Use and Abuse of Antibiotics in Neonatology
Martin Stocker, Lucerne
Jan. 10, 2017 · 2:50 p.m.
467 views
Panel Discussion : Controversies on Use of Antibiotics in Neonatology
Martin Stocker, Christoph Berger, Eric Giannoni, Christoph Bührer
Jan. 10, 2017 · 3:10 p.m.
202 views
Introduction to Christoph Bührer's Presentation
Romaine Arlettaz Mieth , Neonatologist, Zürich, President of the Organizing Committee
Jan. 10, 2017 · 3:47 p.m.
120 views
Evidence-Based Haemodynamic Management in Neonatal Sepsis
Christoph Bührer, Berlin
Jan. 10, 2017 · 3:48 p.m.
638 views
Q&A - Evidence-Based Haemodynamic Management in Neonatal Sepsis
Christoph Bührer, Berlin
Jan. 10, 2017 · 4:16 p.m.
SwissNeoDose Project
Marc Pfister, Ped Pharmacology, UKBB
Jan. 10, 2017 · 4:20 p.m.
271 views

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