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00:00:00
is orders that the remote uh_huh go scary
00:00:09
oh
00:00:12
i i'm an and the seal of it yeah i mean we are
00:00:15
developing an antibody against the run cam for the treatment of cancer
00:00:20
so l. ones cell adhesion molecule is expressed on many to most but the
00:00:25
highest numbers in pancreatic and ovarian cancer
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our first to a target indications
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the expression of that one can is always correlated
00:00:37
with the poor prognosis for the patients
00:00:40
because no one can has multiple roles into war progressions soul
00:00:44
it probably won't to what growth and the test this is formation directly
00:00:49
it contributes to the formation off new plot
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vessels supplying the tomorrow bit nutrients
00:00:57
it also looking chooses resistance to chemotherapy
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and it blocks the immune system from fighting the cancer and
00:01:07
looking at this as solution becomes immediately abbott and so
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when court identified the patients bit than a one can positive to more
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but the suitable companion diagnostic and then treat these patients but an
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antibody that blocks and one came and this should revert
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the functions of everyone came and he too with therapeutic benefit
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and in fact our um licensing partners at the
00:01:39
german cancer research centre have already demonstrated
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preclinical proof of concept in mouse models some nice treat that
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with anti open can antibodies show to reduce to memorise
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and the prolonged survival soul school of course i mean
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such another treatment would have a huge market potential
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and our compound has blockbuster potential already in the first two indications
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we are an experienced team but more than
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fifty years of experience in bringing
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biological compounds from early research into clinical development
00:02:24
and also very important to know that we can work to get up because
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we have done in the past in the management team of s. partake
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we have successfully close to see a round in some of these year and have started our activities
00:02:40
and we're not gonna see you round yeah we are looking for two million
00:02:44
swiss francs to select our clinical candidate molecule if this is interested oh
00:02:51
condor night we are around all day and we'll still have slots in our our meeting schedule
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right a regular high crime
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but uh i one one question is there anybody with a
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question school question i have one of the competition
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actually to our surprise there is no competition really so there's
00:03:16
no other uh i attack of from our company
00:03:21
uh developing an antibody against the one can however it is to not therapeutics well also things that
00:03:27
one can is a is a valuable target and they're developing a cart to you um therapy
00:03:34
for the treatment of new applies to my patients are going to remote thanks again on it so now please please

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