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thank you for this opportunity to that we present this study was done
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by a medical student in the frame of the bachelor said
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comes and it's all a site to maybe make it a virus infection is
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the first 'cause of non genetic in that mirror some surreal deafness
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and soon in the it section can also leaching euro chicken impairments and this risk is dependent
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many factors whether it's a prime infection this assembly activation do it
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has been shown that re infection maybe activation them both lead
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to us into matching protection i also think that it's symptomatic
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new blondes have that to ninety percent chance of developing
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neurology consequently whereas it's only fifteen percent for a symptomatic newborns also
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in your o. g. calls a colour as well influenced
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by the type of lesions and these depend on the moment infection happens
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so as you can see here here are the main brain and emily's sinking seen detection
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in the classification by bach beach and the most of the illusions i've seen
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before twenty four weeks of justice it just doesn't know age we will focus
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on what's meant to disease which has been associated with neurological impairments
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so into excel and there is actually no universal screening for c. m. b.
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during the pregnancy is was the buttons and in two thousand and fourteen
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and they're on target the guidelines regarding the imaging diagnoses
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tools most answers i going to use ultrasound
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and enter i seems to be systematic only when the babies are showing you roger consent
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c. t. scans the band and sometimes and just occasions and cerebral spinal through it is rarely used
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what seems to be always down is the search of hearing impairment and also an eye examination
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so we decided to conduct a study in order to compare the diagnostic
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value of cerebral ultrasound and emma right insane be positive newborns
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also to deter mined the characteristics of might matter disease positive
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and negative patients and to assess this white matter
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by measuring daddy eighty sees in order to going to quantitatively correct to rise to white matter disease
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so with that over not so much not retrospective case control study in as i am
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concerning children born between two thousand and four and two thousand
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and seventeen and they had seen the congenital infection
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and during their into this situation they had both cerebral ultrasound and then uh right
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um we classify them into two groups whether the hot on not
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two regions of whites matter hyper intensity but hey miss them
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um the images from both ultrasound and and the right button allies that too blinded experts
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the character isolate shoes uh according to literature and the mid eighties
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sees when measured into three regions of intrigue of interest
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the temper or front and posterior anderson the bow site as you can see here on this a. b. c. map
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these are the asians on the problems all cost area and supper all
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uh this the that the region but them as well he and these images on t. two sequences
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uh you can see here of all the patient on the right side that there are temporal was much
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a disease or us the rise not on the patient on the left side here as well
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you can see the white matter these these here cost area and will sit in front all
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and this is an a. g. c. map that was generated from the fusion images
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and for the patient on the right side as well we can
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clearly see this hyper intensity here and here as well
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dan or operations we had a thirty eight patients in a population
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and that was not to friends except for gender moguls into white but it's true
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well that's a logical a hearing test and also uh as
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expected um a different spot for some and i'm right
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interestingly we see that there are forty per cent of patients
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during my personally but the difference between the two groups
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concerning the imaging that you'd miss these tools um
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uh we can see that the ultrasound is clearly superior
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for diagnosing kelsey vacation and antique illustrate vascular pretty
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and of course i'm white matter disease that um is um all seen on uh m. right
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if you're not to does this was seen on m. arrive
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this is uh ultrasound but this difference was not significant
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then we measure the eighty seasonal population
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and we can see that the mean values for all all the regions of interest out a ball
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the trash all the special was down for a general neonatal population
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and when we compare the eighty c. valued in white matter disease and what not to
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this is subgroups we see that clearly what matters is subgroups ha ha yep
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uh levels of eighty six and this full the regions of interest
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and even after we're just these measures uh at four gestation on h. one b. and the rightmost on
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and what we know is that these eighty c. levels are clearly a ball
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the ones that we can measure for premature as well around one hundred and eighty
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so in our population we had forty percent of my christopher lee and this was
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not discriminated for whether the kid hard on not what's not to disease
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uh we so wise matter this is in forty five percent off in our population and it was uh
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more diagnosed with emma right but ultrasound and and are are complimentary full
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us to diagnose all this you can be related to normalise
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and the asian majors helped us provide a quantitative confirmation of the whitewater disease
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that fall we would advise a systematic in a rifle all seem to positive
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new balls and these regardless of the symptom all stated that we can
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use the easy measures to get the tailor patients of percentage of treatments
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and as well this study opens up perspectives used white matter disease and eighty smash it to
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try to um cover like the outcome of this case and also to use
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the aces in a combine scoring system for c. n. b. thank you
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which
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yeah
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i had been thinking i had the questions for for all of you
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um who is where the between diseases systematic in right
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in the c. m. v. p. t. b. s.
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does anyone do we need
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uh_huh divided them in in the system and the and the german part is there anyone in
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it would be after what does that would you
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uh_huh
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okay then the other question
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yes now
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yes yes they will be followed up in our development unit uh_huh or from a problem
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three yes uh_huh
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okay thank you

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Conference program

Opening
Matthias Roth-Kleiner, Lausanne
16 Jan. 2018 · 9:34 a.m.
Welcome words
Mathias Nelle, Bern
16 Jan. 2018 · 9:36 a.m.
Personalised prediction of weight changes in the first week of life
Severin Kasser, UKBB
16 Jan. 2018 · 9:41 a.m.
Neurofilament serum levels as biomarker of neuronal injury in very preterm born infants
Antoinette Depoorter, PhD Candidate
16 Jan. 2018 · 9:49 a.m.
Neonatal red blood cell (RBC) transfusion practices in Switzerland
L. Gosztonyi, C. Rüegger, R. Arlettaz, Neonatology USZ
16 Jan. 2018 · 9:58 a.m.
NEO (Neonatal Esophageal Observation) Tube - A feeding tube with monitoring function
Patrizia Simmen, Department of Neonatology, University of Basel Children's Hospital
16 Jan. 2018 · 10:25 a.m.
Less invasive surfactant Application - Pro
Angela Kribs, Köln (DE)
16 Jan. 2018 · 11:33 a.m.
Less invasive surfactant Application - Contra
Sven Schulzke, Basel
16 Jan. 2018 · 11:51 a.m.
Q&A - Less invasive surfactant Application
Panel
16 Jan. 2018 · 12:14 p.m.
Stem cells and birth
Martin Müller, Bern
16 Jan. 2018 · 2:32 p.m.
Stem cells and white matter disease
Raphael Guzman, Basel
16 Jan. 2018 · 3:16 p.m.
Protect the neurons: The challenge of the neonatologist and the researcher
Anita Truttmann, Service de Néonatologie, CHUV
16 Jan. 2018 · 4:12 p.m.

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