Player is loading...

Embed

Embed code

Transcriptions

Note: this content has been automatically generated.
00:00:00
highlighting how important it is to ask critical questions and many first of all i would
00:00:06
like to get under like rips the opportunity to respond to some of the
00:00:11
yeah raise questions no i i think they're raised questions are here
00:00:17
and it's also cannot that said we need for us are
00:00:21
blind date and speaker on the mice controlled trials and so
00:00:27
is is is is is um appoint a one now
00:00:30
this notice come home and there's only one point uh
00:00:35
where i would lie obvious cash and this
00:00:38
is that if um it's a it's a point of giving caffeine oh early or late top
00:00:43
as the um um this ends the study how to study
00:00:47
uh say available studies show that giving so um
00:00:51
given caffeine as and giving coffee in late but always defined as
00:00:57
giving you you in the first three days off life
00:01:00
and in our studies that means that it's well they aim the study most
00:01:06
babies next you paid during the first three days of lies and so they received its
00:01:12
and caffeine at least during this time uh from between knows that it does have
00:01:18
a better to give us a caffeine into if time maybe um saps evenings up tired
00:01:25
we discussed about six point and and and at this time that it's already
00:01:31
nearly ten years ago was an easy um uh uh some of the cool investigators um
00:01:37
by rank right it's can take to give caffeine prophylactic i'll be too intense
00:01:43
not you being already excavated and therefore we
00:01:47
um we get it in the practical
00:01:51
and now now that may today um i would uh give coffee even yeah
00:01:56
at the same time point four balls groups um was
00:01:59
control club as well as uh intervention corp but
00:02:03
um i think they existed intervals thousands a study protocols
00:02:07
have to be discussed um on the um
00:02:11
and uh and situations that rex distant during the period twelve the particle about
00:02:16
k. r. and at this point it was not clear that caffeine
00:02:20
is safe to give your in the first at some hours
00:02:24
of life and yeah i even people um who um what
00:02:29
are uh give as an argument for the other side
00:02:33
um um the sect mcafee in it's so early in the protocol offer you that
00:02:39
so i think um it's it's it's school actually uh uh points it has to be
00:02:44
discussed but not a point to that can be used against please have a seat
00:02:51
the other questions i'm sure there should request
00:02:58
brokerage almost convinced us that uses a good thing and then here comes by and and
00:03:03
uh let me just also make one comment it's always easy to quickly size
00:03:09
individual deeper detail so from a large multi centre trials it's it's very
00:03:14
hard to conducted so obviously i find i try to find
00:03:19
issues yeah but it's very hard to get twelve centres in one boat and do the same thing
00:03:26
yes and and and to add to my opinion says point of coffee in it's really a very
00:03:30
important point caffeine is um is a tax it
00:03:34
is um the use to um very widely
00:03:37
not quality and at some human to we're convinced
00:03:40
that did at least safe um and uh
00:03:45
will be and convinced that it may be better to be viewed as
00:03:48
early as possible um uh i i'm a little bit afraid
00:03:53
it's it's actually in and may be also a mistake and said
00:03:56
this is it does not souls saved to give it
00:04:00
it's only as we do it uh nowadays in some cases
00:04:04
so i think caffeine is another track and as
00:04:07
a a question besides believe that mess that as we said we have had that has to be studied
00:04:14
i mean i think i mentioned about early application off of from a post hoc analyses
00:04:19
of the cap trial so this was not the primary purpose was not
00:04:23
comparing um th initiation of sticking to therapy it's a postal canals
00:04:30
and so will you please yes thank you very much it's very very nice discussion these arguments are very different
00:04:39
and the light your comment concerning the control group so it's always a problem portugal control group and
00:04:45
a change to to use hinge users of optimal choosing one
00:04:50
consult for or she can should be changed again
00:04:54
course uh uh just to give you an argument in your trial uh
00:04:58
you mentioned the side effects of the user meaning ready cody you're
00:05:03
up here and so on and there are some side effects yes and uh and there are some side effects that are yeah
00:05:10
i'm already mentioned set um the side effects uh also the painting experience
00:05:16
of the person from the put your end of the wood
00:05:19
fence opposite him uh put fee guises and i'm home when we
00:05:24
start it was uh my descendants right it's some of the
00:05:27
does one more in somewhat less experienced and then if a a point
00:05:33
just reached about to send us a s. experience this um this
00:05:39
mechanical ventilation and interfere into patient s. this these are then we can really compels
00:05:44
a and a sample scripts accountancy s.s side effects that um liza is
00:05:52
less injuries face if i'm convinced that it is less invasive but it's not really
00:05:59
non invasive and um it would be um i'm actually go
00:06:04
to a to have a and that's that's that's
00:06:06
it that is really known and invasive and and i
00:06:12
i think um is so so we discussed
00:06:15
it's also a discussion of a philosophic and you're
00:06:19
mention sex um has a um control or
00:06:23
has not so optimum mechanical ventilation me that
00:06:29
an and i think so and uh
00:06:31
i think that it's um also problem to set up in all its send us so
00:06:36
optimal mechanical ventilation i bought myself a is
00:06:42
that a a itself um knows
00:06:46
best what to do and spontaneous preceding if it is sufficient the base
00:06:55
always better than any mechanical ventilation and so
00:07:00
i think the discussion um of um
00:07:04
what about liza is also a discussion about this philosophy
00:07:08
and and it was it says also um
00:07:12
when i meant concerning um so t.
00:07:17
and it's the parents and we are very more confident in the value p.
00:07:24
of the infant if the infant is contained see policing i um
00:07:29
like if this case the story of the first infantry
00:07:32
outperformed like lisa and um for this parents it was very
00:07:37
important sets but they people spontaneously precinct wasn't very important
00:07:43
point giving the confidence yeah in the via b. t. of c. infant and and
00:07:49
in our team um seven was also a change from changing so that's the um
00:07:57
the minute it consoling say essex and then we
00:08:02
started with lisa before introduction of fees are
00:08:07
many of the noises let's say it is not
00:08:11
ethical tool to preach base is a gas station and age
00:08:16
or of twenty three weeks that after the introduction of realise that was a baby
00:08:23
that into into battle spontaneously producing this discussion disappear anytime
00:08:29
i think since these are or points that
00:08:32
we have also to have in mind if we discuss the parties and i think that's
00:08:36
a very important point so i think it's not the board shifted administration but it's the board
00:08:42
ventilation into the little room in the control group the problem is usually group is
00:08:48
it's actually been should be it should fit complex to beat us nothing about ventilation
00:08:53
due to function with the injury prone choose the two then surely the remote to going to do it i
00:08:58
mean none of those studies were done in the delivery room yeah everything was done later so yeah
00:09:03
but but but nevertheless see these ensures not really unsure
00:09:06
because it's part of integration yeah engine between and
00:09:11
i'm still i think that's an important difference
00:09:18
okay thank you maybe have one more question because we need to move on to the business meeting afterwards
00:09:25
uh_huh
00:09:29
okay maybe then i have one question um do you think videos just uh
00:09:33
devices will make me so even if these or and less invasive
00:09:40
is there anything on the horizon
00:09:44
oh yeah if i thank you very much conclude their assertion

Share this talk: 


Conference program

Opening
Matthias Roth-Kleiner, Lausanne
16 Jan. 2018 · 9:34 a.m.
Welcome words
Mathias Nelle, Bern
16 Jan. 2018 · 9:36 a.m.
Personalised prediction of weight changes in the first week of life
Severin Kasser, UKBB
16 Jan. 2018 · 9:41 a.m.
Neurofilament serum levels as biomarker of neuronal injury in very preterm born infants
Antoinette Depoorter, PhD Candidate
16 Jan. 2018 · 9:49 a.m.
Neonatal red blood cell (RBC) transfusion practices in Switzerland
L. Gosztonyi, C. Rüegger, R. Arlettaz, Neonatology USZ
16 Jan. 2018 · 9:58 a.m.
NEO (Neonatal Esophageal Observation) Tube - A feeding tube with monitoring function
Patrizia Simmen, Department of Neonatology, University of Basel Children's Hospital
16 Jan. 2018 · 10:25 a.m.
Less invasive surfactant Application - Pro
Angela Kribs, Köln (DE)
16 Jan. 2018 · 11:33 a.m.
Less invasive surfactant Application - Contra
Sven Schulzke, Basel
16 Jan. 2018 · 11:51 a.m.
Q&A - Less invasive surfactant Application
Panel
16 Jan. 2018 · 12:14 p.m.
Stem cells and birth
Martin Müller, Bern
16 Jan. 2018 · 2:32 p.m.
Stem cells and white matter disease
Raphael Guzman, Basel
16 Jan. 2018 · 3:16 p.m.
Protect the neurons: The challenge of the neonatologist and the researcher
Anita Truttmann, Service de Néonatologie, CHUV
16 Jan. 2018 · 4:12 p.m.

Recommended talks

Q&A - Association of Axonal Injury and Preeclampsia
Katrina Evers, Neonatology UKBB
10 Jan. 2017 · 9:44 a.m.