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Q&A : Relationship of diet to gut microbiota diversity, stability and health in older people
Paul O'Toole, University College Cork, Ireland
Thursday, Oct. 23, 2014 · 4:27 p.m. · 07m 37s
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Interesting find a to a big relation I
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think what we bought a clinical
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significance of these groups. I don't
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know actually what is long stay
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reputation population that's a come
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completely it a S it's about the
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diagnosis to be in the recognition get
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it. And maybe you will have like
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fracture decide all fashion or in the
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movie are and so what it provides a
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fantastic viability of measurements wow
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why did you do you get to choose what
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to to select to make a selection of a
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limited number of disease in elderly
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people and to compare my computer in
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this groups of patients to you got
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people having the same deceased I agree
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with you but we have some of the data
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we are asking for reasons that I'm I
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haven't presented. It's not just willy
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nearly heterogeneous group of people
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along stay we have the data and we can
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look for association between people or
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say physically okay but have to mend
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yeah or paypal or completely physically
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incapacitated. And we have that
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granularity and work week and have
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tested I didn't report for reasons of
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time also this was the stratification
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which was deciding two thousand seven
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and we got in two thousand next and
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since then we are going from five
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hundred individuals two thousand with
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the much more target stratification
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based on the clears associations which
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we saw in the primary cross sectional
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analysis Oh Oh hell with this is yeah
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well I hope those oh sorry for this
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most likely they this is most likely
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that both once that's got to be like
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that that's the least. I saw was the
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what you exactly this oh yeah you try
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to and each other or talk we almost
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have to be completely better to I wanna
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see is that we we we want for my guess
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is that us. And I I I all well I I
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think that's that that that idea have a
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couple hours by bus you know you know
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this is a rapidly. So this is a fancy
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we just leave this is an enormous
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functions of the and you have the was
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that it okay thank you for your
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energetic and country I also marker why
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does that yeah you know how are you
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gonna use oh oh the do you the the
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primary value contribution was to
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remind me to say that we have more
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fully where Polly pharmacy and we've
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controlled all of these correlation
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analyses for probably pharmacy. So
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first of all we have control for
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medications a confounding factor in
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other words just somebody's taking on
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steroid landing from tree drugs we
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adjust the statistical model
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accordingly all cup probably pharmacy
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is a fact of life of all these
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individuals we knew with from day one I
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forgot to say that apologise but it has
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been taken care. Thank you RTV it's for
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millions of these stability of the
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Michael by Norman their elderly
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subjects in battery park a spark he
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presented his infant study. Um which
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show that then we deliver Indians
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tended to regress there to the
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rotational for up over the course of
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course the first your wife in one could
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speculate it's was there Michael why
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are profiles that for the rest of their
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LY you got a in any of your O four
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sisters who was delivered actually in
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who was delivered by C section might
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yeah oh yeah yeah a lot of these folks
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can't remember long birthday I don't
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know so the answer is no we we actually
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wondered what were some of these
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environmental science we initially
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thought it might have an affect a one
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particular facility but the trends are
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related today occurred and lots of
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different lawn care facility so it's
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it's not simply an issue of sanitation
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requirements exposure which explains
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the variation and Mike about yeah O
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well OBU N. B. C. G. is it spongy sure
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from normality clear to you and to
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become dependent. And someone I I'd be
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cool okay with a specific disease. And
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don't go someday on them be cool yeah
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infrared port but living in the
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community not enough signal. And to see
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what are instead of using the
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facilities are somewhat sequential
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Nicole yeah only we call you're gonna
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be one of the of the for the for the
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speaker that was an obvious question
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and I can I give the astra today but
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it's part of the target recruitment
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which we are now doing to look at the
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longitudinal and changes in frailty a
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Mike about in the community yeah but I
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I Well I mean initially. And one issue
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I I kind of contradiction with the
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public function because most of the
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activity may I think this has and
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problems of constipation and this can
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change completely there like a regular
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pad and also I just maybe because the
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right location it's a great question
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and we have previously reported in IBS
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association to microbiologist and
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intestine transit time we have not been
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able to find us in these elderly
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subjects no clear so zero or increased
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transit time causes blah blah blah we
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haven't seen the yeah well we yeah we
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use it this is my third down that was
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good because that that takes into
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account do you probably see different I
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this is secure since these going on you
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just one way to a big would be know
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coherently used a week they must I have
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done that in the it but we would we're
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doing those analyses as we speak yeah
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thank you yeah yeah yeah yeah oh in the
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I don't know so severely what would you
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have styles in because they're one of
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the problems with that thought research
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methods here we can sell "'em" version
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if you have a measurements of sacred.
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So fully role or or or stopped wheezing
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stuff. So oh it would help you to get
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evidence what we have four blows with
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different roles but we will also hope
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to do full serum at Avalon mix so we
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can agnostic lee look for extreme by
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markers and like about the changes
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thank you very much now we like that
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that collected to my glasses on TV but
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there but I know a of suggested from
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