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Are there many questions one here one
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here we why we must have time for some
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questions. So please we question
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Christine I really need you know if you
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want to be no one once we on TIBO three
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months though they can become
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unification Yeah so what we did was we
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we we actually use an APP not a mouse.
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And in fact that's why the papers not
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coming up image is read the paper this
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paper to show which is also a positive
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integer for six months three revisions
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in any end because we "'cause" when we
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did EPP knockouts. We had a trend
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toward them be more susceptible to
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infection but a significance think is
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as you try to argue to them you know
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it's incredible redundancy in need a
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new system you can't you can't go wrong
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with it. So we were seeing other any
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and you can I think about thirty seven
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defendants going up any P knockout
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mice. So they had some susceptibility
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but it was a significant. So I think I
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want you cannot express a data in CTO
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protection. But we not only PP you get
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some reduction in susceptibility but we
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don't see I think it doesn't let you
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see the whole thing and that's why it's
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coming up the size transitional Madison
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and that image. Oh I am too nasty
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nutrition counsellor oh yeah people are
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also said it's hard to predict anything
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in especially future so I have a
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question how does low social economic
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stages critic you draw fire isn't what
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it is that in a few months not myself
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Well I not my area of of of of
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expertise but there are studies to
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suggest that for sure and I think we
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doubts that you just think not only
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about aspects of education but aspects
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of hygiene because the the most
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probably the the biggest source of
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chronic infection information the body
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you columns. Um I'm taken much better
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care my teeth now tonight so this data
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by the way but also gonna think about
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about a a microbiology die have that
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thing bugs in the right I'm this is our
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one china territory we're actually
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doing experiment now. So in hour
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catalogue in the microbe by of the
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brain because it's small amounts of yet
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to do are anything to do it is very
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small amounts. But from normal you know
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a young to help yelled off time is is
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they're changing them at the bottom of
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the brain could explain somebody
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results and stuff oh Reduces schools
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the how I exclaimed in the the
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phenomena that you talked about really
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or which she is we can find people at
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lowe's but okay we don't have to use
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your series norms of course diseases
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because there's no point in her. So I
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was happy with it I mean why don't they
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have a bacterial infection yeah what I
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will plaques the security that and then
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I say no yeah I mean so these were
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people where you see I mean that's
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pretty we're we we found sixteen brains
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around the country that had high price
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levels or in some cases backstage five
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or six tangles. And it that it is not
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to mention that was real nation. I
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guess if they were living you know
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several hundred one thousand years ago
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they might not have supplied because
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maybe they bring I'd of had less
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ability to fight infection because
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might also also less likely "'cause" it
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invitations to go to that ignorance
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assignment or they put in today's
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society the we live there probably just
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when challenged unjust and that's all
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they had a good afternoon system
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ability yeah I was wondering actually a
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pretty dress reduce in yeah increase
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the consequences of our actions. So
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some drive to talk about yeah I yeah so
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I skipped past sliding sometime base
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right sane is if you use an example way
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drawing style a to do cluster but don't
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like out and god knows don't do not
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that solution because you can't control
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that afterwards. So if you're gonna use
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it is it is heavily games dissenters
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maybe a civilisation. But at the
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vaccinations probably not a good idea
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oh what's that S so at the end of the
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cities are they you need to read your
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conclusion was that a clinical
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diagnosis right any stacker yes. So am.
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I using here. I lost sight to us steady
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fixations away or we just give it want
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to be on a semi up till now we had that
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we only accept jeans which is a tiny is
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you know fraction of a percent of GD
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yeah they probably for which is highly
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addictive but you need the rest of
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these genes together with it you Ross
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only gave us the genes only
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transitioning out into the whole genome
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sequencing. So I won't be publishing
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with that holding know paper you know
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just tons of excel seats of the
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variance that we found in those jeans.
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And the ones that were so she really DR
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gonna maybe some of those at some point
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will be on the chip altogether we would
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test for maybe a hundred two hundred or
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even the thousand functional brilliance
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and empirically determined which ones
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you determined respect that still work
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in progress people over there was just
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beginning to to do the base these no
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because you can you can you actually go
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to the dock after forty years old you
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get any of its name family you you can
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use it as high we do spinal tap your
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proselytise hire maybe that that's
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these protests but I was even easier
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ones that comes online. And and then
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you say that you're the seventy
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percentile finger age for how much time
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you have entangled we can tell you
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gonna get a sinus trouble your wrist
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just like my cardiologist says you have
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a family history of heart disease you
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have high cholesterol and taken apart
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or so if you have a safe draw like that
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that you can take to bring your family
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down and you know yeah white tie and
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you have about Marcus already there why
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not do it. So you do maybe start doing
00:06:08
that after forty years all the future
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that's as possible yeah yeah I know
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going back to the three dimensional
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tissue culture I just had a question
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regarding we're rewriting engine target
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that this is a theory research just
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want to ask if the activity patterns
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you Sir as a normal in the three
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dimensional culture for before the fax
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number to look like you were looking
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very early in the culture in since
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we're considering stream cease for yeah
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yeah I could the dynamics in plano
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formation and as we look at a very
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early difficulties before any platform
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to sit there are differences yeah so
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that's a great question we have to do
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more time line on that but at any rate
00:06:52
so other countries that's when you
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start seeing the fire is down at that
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point you don't have plaques you have a
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beta like numbers lot and and you also
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start C passport are detergent system
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again as but no plaques and tangles
00:07:04
effort that's been used asking
00:07:05
dysfunction okay I think we all know
00:07:14
just want to dress with that value

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Conference Program

Introduction to the 12th Nestlé International Nutrition Symposium
Thomas Beck, NRC Director
22 Oct. 2015 · 8:57 a.m.
418 views
Introduction to Session I - Cognitive & Brain Development
Susan Gasser, Friedrich Miescher Institute, Basel, Switzerland
22 Oct. 2015 · 9:04 a.m.
The development of a healthy brain
Michael Gazzaniga, University of California, Santa Barbara, USA
22 Oct. 2015 · 9:16 a.m.
221 views
Q&A - The development of a healthy brain
Michael Gazzaniga, University of California, Santa Barbara, USA
22 Oct. 2015 · 9:56 a.m.
Early influences on brain development and epigenetics
Stephen G. Matthews, University of Toronto, Canada
22 Oct. 2015 · 10:49 a.m.
Q&A - Early influences on brain development and epigenetics
Stephen G. Matthews, University of Toronto, Canada
22 Oct. 2015 · 11:29 a.m.
Building the physiology of thought
Rebecca Saxe, Massachusetts Institute of Technology, Cambridge, USA
22 Oct. 2015 · 11:38 a.m.
154 views
Q&A - Building the physiology of thought
Rebecca Saxe, Massachusetts Institute of Technology, Cambridge, USA
22 Oct. 2015 · 12:10 p.m.
Introduction to Session II - Cognitive Decline
Kathinka Evers
22 Oct. 2015 · 2:02 p.m.
Brain health & brain diseases - future perspectives
Richard Frackowiak, CHUV University Hospital, Lausanne, Switzerland
22 Oct. 2015 · 2:11 p.m.
Alzheimer's disease: genome-wide clues for novel therapies
Rudolph E. Tanzi, Massachusetts General Hospital, Charlestown, USA
22 Oct. 2015 · 3:15 p.m.
Q&A - Alzheimer's disease: genome-wide clues for novel therapies
Rudolph E. Tanzi, Massachusetts General Hospital, Charlestown, USA
22 Oct. 2015 · 3:59 p.m.
Immunometabolic regulators of age-related inflammation
Vishwa D. Dixit, Yale School of Medicine, New Haven, USA
22 Oct. 2015 · 4:21 p.m.
Q&A - Immunometabolic regulators of age-related inflammation
Vishwa D. Dixit, Yale School of Medicine, New Haven, USA
22 Oct. 2015 · 4:59 p.m.
Introduction to Session III - Nutrition & Cognitive Development
Pierre Magistretti, KAUST, Thuwal, Saudi Arabia and EPFL, Lausanne, Switzerland
23 Oct. 2015 · 9 a.m.
Energy metabolism in long-term memory formation and enhancement
Cristina M. Alberini, The Center for Neural Science, New York University, USA
23 Oct. 2015 · 9:16 a.m.
129 views
Q&A - Energy metabolism in long-term memory formation and enhancement
Cristina M. Alberini, The Center for Neural Science, New York University, USA
23 Oct. 2015 · 9:53 a.m.
Building the costly human brain: implications for the evolution of slow childhood growth and the origins of diabetes
Christopher Kuzawa, Northwestern University, Evanston, USA
23 Oct. 2015 · 10:29 a.m.
Q&A - Building the costly human brain: implications for the evolution of slow childhood growth and the origins of diabetes
Christopher Kuzawa, Northwestern University, Evanston, USA
23 Oct. 2015 · 10:57 a.m.
Nutrition, growth and the developing brain
Prof. Maureen Black, University of Maryland, School of Medicine, Baltimore, USA
23 Oct. 2015 · 11:09 a.m.
Q&A - Nutrition, growth and the developing brain
Prof. Maureen Black, University of Maryland, School of Medicine, Baltimore, USA
23 Oct. 2015 · 11:49 a.m.
Introduction to Session IV - Decline & Nutritional Intervention
Tamas Bartfai, The Scripps Research Institute, La Jolla, USA
23 Oct. 2015 · 12:48 p.m.
On multi-domain approaches for prevention trials
Miia Kivipelto, Karolinska Institutet, Stockholm, Sweden
23 Oct. 2015 · 1:04 p.m.
Q&A - On multi-domain approaches for prevention trials
Miia Kivipelto, MD, PhD, Karolinska Institutet
23 Oct. 2015 · 1:39 p.m.
Methodological challenges in Alzheimer clinical development
Lon S. Schneider, Keck School of Medicine of USC, Los Angeles, USA
23 Oct. 2015 · 1:49 p.m.
Q&A - Methodological challenges in Alzheimer clinical development
Lon S. Schneider, Keck School of Medicine of USC, Los Angeles, USA
23 Oct. 2015 · 2:32 p.m.
We are what we remember: memory and age related memory disorders
Eric R. Kandel, Columbia University, New York, USA
23 Oct. 2015 · 3:03 p.m.
138 views
Concluding Remarks
Stefan Catsicas, Chief Technology Officer, Nestlé SA
23 Oct. 2015 · 3:50 p.m.